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姓 名：陈端端 学 历：博士 职 称：讲师 院系部门：动物医学系 专 业：动物医学 联系方式：dduanchen8085@163.com chenduanduan@lcu.edu.cn |
个人简介
陈端端，男，1992年1月生，山东新泰人，2015年毕业于潍坊学院，获农学学士学位；2016考入山东农业大学，2019年获硕博连读机会，2022毕业于山东农业大学生命科学学院，获理学博士学位，同年7月进入聊城大学 农学与农业工程学院工作。主要从事水生动物先天免疫，虾蟹主要细菌性病害的致病机制和弧菌噬菌体制剂的研发与推广应用。中国生物化学与分子生物学会会员、山东省科技特派员、山东省免疫学会兽医免疫专业委员会委员。代表作发表在《Ecotoxicology and Environmental Safety》、《Aquaculture》、《Aquaculture Reports》、《Fish & Shellfish Immunology》、《中国兽医学报》和《中国预防兽医学报》等杂志。
教学工作
参与承担研究生《分子流行病学》、《蛋白质研究技术》，本科生《普通动物学》、《微生物实验》等课程的教学工作。
研究方向
1. 弧菌的分离鉴定及致病机制研究
2. 副溶血弧菌与噬菌体相互作用机制研究
3. 水生动物先天免疫防御机制研究
4. 淡水虾蟹主要细菌性病害的致病机制研究
科研项目
1. 聊城大学博士科研启动资金：噬菌体与携带AHPND毒力基因的副溶血弧菌相互作用的转录机制研究 20万 主持
2. 优质高抗对虾突破性新品种选育 2019LZGC014 84万 参与
3. 藕渔共生生态农业增效技术集成与示范 2019GNC20920 5万 参与
4. 澳洲淡水龙虾的引种驯化繁殖与产业化开发研究 2017LZN010 20万 参与
代表性成果
1. Zhiwei Wang, Hui Wang, Duanduan Chen*, Yubao Li*., Genomic characterization and comparative genomic analysis of pathogenic Vibrio isolated from aquaculture-grown white-leg shrimp (Penaeus vannamei) in Guangdong and Jiangsu, China. Aquaculture, Pub Date : 2023-10-31 , DOI: 10.1016/j.aquaculture.2023.740302. 通讯作者 (IF=4.5，一区)
2. Duanduan Chen, Zhiwei Wang, Shengliang Cao, Jianbiao Lu, Cheng Liu, Lingling Yang, Xusheng Du, Hui Wang, Yubao Li., Molecular characterization and functional analysis of interferon regulatory factor-4 in the Red Claw Crayfish (Cherax quadricarinatus). Aquaculture Reports Pub Date: 2022-12-26 , DOI: 10.1016/j.aqrep.2022.101456. (IF=3.7，二区 )
3. C. Wang, P. Li, L. Guo, H. Cao, W. Mo, Y. Xin, R. Jv, Y. Zhao, X. Liu, C. Ma, D. Chen*, H. Wang*, A new potential risk: The impacts of Klebsiella pneumoniae infection on the histopathology, transcriptome and metagenome of Chinese mitten crab (Eriocheir sinensis), Fish & Shellfish Immunology (2022). Pub Date : 2022-11-07 , DOI: 10.1016/j.fsi.2022.11.010. 通讯作者 (IF=4.7， 二区)
4. Chen, D., Wang, C., Guo, L., Mo, W., Xin, Y., Cao, H., Mu, C., Zeng, Y., Wang, H., 2022. A comprehensive analysis based on histopathology, metabolomics and transcriptomics reveals molecular regulatory mechanisms of the red claw crayfish (Cherax quadricarinatus) in response to acute hepatopancreatic necrosis disease (AHPND). Aquaculture, Pub Date : 2022-04-07 , DOI: 10.1016/j.aquaculture.2022. 738225. (IF=4.5, 一区)
5. Chen, D., & Wang, H. (2022). Redclaw crayfish (Cherax quadricarinatus) responds to Vibrio parahaemolyticus infection by activating toll and immune deficiency signaling pathways and transcription of associated immune response genes. Fish & Shellfish Immunology, 127, 611-622. Pub Date : 2022-07-06 , DOI: 10.1016/j.fsi.2022.06.069. (IF=4.7，二区)
6. Chen Duanduan, Guo Leifeng, Wang Chen, Cao Hongzhen, Mo Wei, Xin Yunteng, Zeng Yongqing, Wang Hui. 2022 Comparative transcriptomic and metagenomic analyses reveal key factors affecting the growth rate of Red Swamp Crayfish （Procambarus clarkii）[J] Aquaculture Reports. Pub Date : 2022-03-19 , DOI: 10.1016/j.aqrep.2022.101098. (IF=3.7，二区)
7. Chen Duanduan, Guo Leifeng,Yi Cao,Wang Shouquan,Ru Yuanyuan,Wang Hui. 2021. Hepatopancreatic transcriptome analysis and humoral immune factor assays in red claw crayfish （Cherax quadricarinatus） provide insight into innate immunomodulation under Vibrio parahaemolyticus infection[J]. Ecotoxicology and Environmental Safety. Pub Date : 2021-04-27 , DOI: 10.1016/j.ecoenv.2021.112266. (IF=6.8，二区)
8. Guo Leifeng, Zhou Min, Chen Duanduan, Yi Cao, Sun Bing, Wang Shouquan, Ru Yuanyuan, Chen Hongju, Wang Hui. A new insight to characterize immunomodulation based on hepatopancreatic transcriptome and humoral immune factor analysis of the Cherax quadricarinatus infected with Aeromonas veronii.[J]. Ecotoxicology and environmental safety. (IF=6.8)
9. Yi Cao, Lv Xiaoting, Chen Duanduan, Sun Bing,Guo Leifeng, Wang Shouquan, Ru Yuanyuan, Wang Hui, Zeng Qifan. Transcriptome analysis of the Macrobrachium nipponense hepatopancreas provides insights into immunoregulation under Aeromonas veronii infection[J]. Ecotoxicology and Environmental Safety. (IF=6.8)
10. Bing Sun, Huan Luo, Shuo Zhao, Xiaoting Lv, Cao Yi, Duanduan Chen, Leifeng Guo, Hui Wang, Qifan Zeng. 2020 Characterization and the role of α2-macroglobulin from Macrobrachium nipponense in response to ammonia-N stress[J]. Aquaculture. (IF=4.5)
11. Cao Hongzhen, Chen Duanduan, Guo Leifeng, Jv Rong, Xin Yunteng, Mo Wei, Wang Chen, Li Pengfei, Wang Hui. Effects of Bacillus subtilis on growth performance and intestinal flora of Penaeus vannamei[J]. Aquaculture Reports. (IF=3.7)
12. Guo, Leifeng, Sun, Bing, Chen, Duanduan, Yi, Cao, Teng, Jian, Yu, Jielun, Wang, Shouquan, Ru, Yuanyuan, Wang, Hui. 2020.Characterization of a novel ADP-ribosylation factor gene from Macrobrachium nipponense and its response to ammonia nitrogen stress. Aquaculture Environment Interactions. 2021, 13, 165-175. (IF=3.1).
13. 陈端端,刘伟,孟德志,许文萍,杨玲玲,柴同杰,王海荣.新西兰兔产气荚膜梭菌性腹泻引起的脏器损伤和肠道菌群分析[J]. 中国兽医学报. 2019(12)
14.《小龙虾生态养殖技术有问必答》副主编 中国农业出版社, 2020.07, ISNB978-7-109-27128-9
友情链接：
国际噬菌体研究中心